Sandstorm describes how DMs can create adventures and even campaigns set in a desert or wasteland environment. The book details many hazards that are associated with real-life dangers to desert travelers. Furthermore, Sandstorm corrects many false ideas about deserts, such as the belief that quicksands are commonly found in the desert; the book explains that quicksands require water to form, and are usually found near an oasis, although quicksands are still rare even there. The book gives ideas for DMs as well as players in using new prestige classes and new races. In addition, book references several 3rd edition books, such as Deities and Demigods. At the beginning of the book, examples of wasteland areas found in the campaign settings of Greyhawk and the Forgotten Realms are given.

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