Thistle might refer to:
- House Thistle, a noble Cormyrean family.
- Thistle, a type of common flowering plant.
- Thistle, a hamlet in Featherdale.
- Thistle, a 15th century DR clerk from Phandalin.
- Thistle-tree, a species of tree found in the Spiderhaunt Woods.
- Thistle Thalavar, granddaughter of Lady Nettel Thalavar of Westgate.
- Thistfedew Vine, a dryad innkeeper from Ravens Bluff.
- The Year of the Thistle, 885 DR.
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